Positions Available

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Opportunity: A postdoctoral fellow position is available immediately in the Wilson laboratory at the Center for Regenerative Medicine (CReM) of Boston University and Boston Medical. We are seeking recent PhD candidates with research interests in human ESC/iPSC differentiation and disease modelling. Candidates enthusiastic about understanding the genetic and epigenetic basis of obstructive lung disease with a focus on lung epithelium are particularly encouraged to apply.

Duties and Responsibilities: Qualified candidates will work in a tight-knit research group with scientists at various training levels focusing on diverse projects related to stem cell and developmental biology.

Basic Qualifications: Applicants must have a Ph.D. in biological science or closely related field and relevant laboratory experience, including familiarity with tissue culture techniques. Successful candidates will be dedicated, creative, self-motivated critical thinkers with strong written and verbal communication skills.

Additional Qualifications: Ph.D or M.D. in biological science or a related field is required. The successful candidate should be able to manage multiple detail-oriented tasks with minimal supervision, capable of trouble-shooting and critical thinking, self-motivated, dedicated and creative.

Contact: Please forward contact details and a current CV/resume to Dr. Andrew Wilson at awilson@bu.edu
More information: https://sites.bu.edu/wilsonlab

Opportunity: A position as a postdoctoral fellow is immediately available in the laboratory of Gustavo Mostoslavsky, M.D., PhD at Boston University/Boston Medical Center at the Center for Regenerative Medicine (CReM). The position is in the field of stem cell biology, iPSC and differentiation towards T/NK cell lineages, and is a great opportunity for a motivated individual interested in gaining experience, technical expertise and a publication record for a career in cutting edge research.

Duties and Responsibilities: Highly motivated, successful candidates will implement and coordinate ongoing research projects as well as design and direct novel strategies utilizing iPSC modeling of T cell specification. Applicants with technical expertise related to iPSC biology, gene editing and T cell development are preferred. Familiarity with procedures including but not restricted to plasmid and genomic DNA isolation, cloning, cell culture, PCR, blotting, various tissue culture procedures, and molecular biology techniques would be helpful. Candidate will also be required to work independently as well as part of a team.

Basic Qualifications: Relevant laboratory experience; especially familiarity with molecular biology, biochemistry, and tissue culture techniques is necessary.

Additional Qualifications: Ph.D or M.D. in biological science or a related field is required. The successful candidate should be able to manage multiple detail-oriented tasks with minimal supervision, capable of trouble-shooting and critical thinking, self-motivated, dedicated and creative.

Contact:  Please forward contact details and a current CV/resume to Dr. Gustavo Mostoslavsky at gmostosl@bu.edu

More information: www.mostoslavskylab.com

Opportunity:The Murphy Lab is looking for an individual who shares our excitement for stem cell biology and blood development. Specific skills and personal attributes that we hope to find in a candidate are a strong interest in stem cell research and molecular biology, expertise in cellular biology, immaculate organizational skills with exquisite attention to detail, multi-tasking ability and computer and technological savviness.

Duties and Responsibilities: This person will assist in performing experiments, including the maintenance of stem cell lines, and recording and analyzing data. Other specific duties include basic laboratory maintenance, ordering and preparing laboratory reagents and performing routine Mycoplasma screenings.

Basic Qualifications: Bachelor’s degree, preferably in biology or a related field; experience with wet lab work (standard molecular techniques is a plus; excellent organization skills, and proficiency with basic computer software.

Additional Qualifications: While expertise in molecular biology, viral vector production and mouse handling are considered a plus, enthusiasm and willingness to learn can make up for lack of experience in these areas. Ideal candidates should demonstrate good team-working abilities and strong collegiality, as they will be part of a multidisciplinary network consisting of over 60 scientists from seven neighboring laboratories at the center.

Contact: Please forward a cover letter and a current CV/resume to Gabrielle Cockerham at gabbyac@bu.edu

More information: www.murphylaboratory.com

Opportunity: Are you a gene editor who wants to focus on editing stem cells in a warm, welcoming environment filled with collaborative teammates? Come join us in the Kotton Lab at the Center for Regenerative Medicine (CReM) as we pursue our mission of editing iPSCs for lung disease modeling and future therapies. This staff scientist will join an interdisciplinary team working with induced pluripotent stem cells (iPSCs) – a great opportunity to further develop technical and team building skills, and a chance to share your talents with the world as we share your edited cells with the global research community.

Duties and Responsibilities: Successful candidates will work independently, and as part of a team focused on designing and deploying gene editing technologies (e.g. CRISPR-Cas9) to edit the human or mouse genome in pluripotent stem cells in culture.  Applicants with technical expertise related to molecular biology, plasmid cloning, and cell culture are preferred. The CReM and Boston University welcome applicants from diverse backgrounds!

Basic Qualifications: Applicants must have a Ph.D. in a biological science (or closely related field) and relevant laboratory experience, including familiarity with molecular biology and tissue culture techniques.

Contact:  Please forward contact details and a current CV/resume to mnarayan@bu.edu

More information: www.bumc.bu.edu/kottonlab

Opportunity: The Wilson Lab has an open position for a laboratory technician/lab manager. Our lab utilizes patient-derived stem cells to model genetic lung and liver diseases. You will learn a wide variety of techniques, including stem cell tissue culture, CRISPR/Cas9-based genomic editing of patient-derived stem cells, DNA and RNA extraction and manipulation, qPCR, protein analysis, cloning, and other molecular biology skills.

Duties and Responsibilities: Your time will primarily (~75%) be spent performing experiments with the remainder spent on administrative responsibilities.  You will work as part of a highly motivated, fun, and successful team in an outstanding environment!

Basic Qualifications: Bachelor’s degree; Lab experience helpful but not required. A high priority is placed on organizational and communication skills together with ability to work as part of a team. A 2-year commitment is required.

Additional Qualifications: Individuals with an interest in molecular biology research or medicine as a future career are encouraged to apply.

Contact: Please forward a cover letter and a current CV/resume to Gabrielle Cockerham at gabbyac@bu.edu

More information: www.wilsonlaboratory.org

This position is a great opportunity for a motivated individual interested in gaining experience and technical expertise in an exciting research field within the Gouon-Evans Laboratory in the Center for Regenerative Medicine (CReM) and Boston University School of Medicine.

Duties will include conducting supervised bench-top experiments on liver regeneration, stem cell lines, mouse colony maintenance, and carrying out basic lab manager duties. Your time will primarily be spent performing experiments and you will work as part of a highly motivated, fun, and successful team in an outstanding environment! A 2 year commitment is expected.

Duties and Responsibilities: The candidate will work closely with lab members to support the different research projects. The majority of techniques involve working with laboratory mice, harvesting and analyzing mouse tissue and cell culture of mouse and human stem cell lines (such as induced pluripotent stem cells). Specifically, this will include liver tissue collection, sectioning, immunostaining, liver function and regeneration assays, as well as stem cell culture for maintenance and expansion, basic characterization using PCR, cDNA preparation, Real-time PCR and immunostaining. He/she will maintain the various mouse colonies that will require handling mice, preparing tail DNA and genotyping by PCR. In addition, he/she will be in charge of ordering and purchasing and maintaining the lab stocks. Organization skills, ability to work well with others, and willingness to learn lab techniques are key.

Qualifications: Bachelor's degree in Biology or a related field is required. Mouse work and familiarity with routine laboratory tasks are highly desirable. Cell culture is desired but not required. The successful candidate will be a motivated person with careful attention to detail, excellent organization and documentation skills.

Contact: Please forward a cover letter and a current CV/resume to Gabrielle Cockerham at gabbyac@bu.edu

More information: https://www.bu.edu/dbin/stemcells/lab_gouon_evan.php

Opportunity: The Serrano Lab is seeking a curious, thoughtful and motivated laboratory technician/manager to join the lab at the Center for Regenerative Medicine (CReM), Boston University. The Serrano Lab is a young yet promising lab that offers career development opportunities and strong mentorship in a thriving scientific community.

The Lab: The Serrano Lab studies neurodevelopment and cardiovascular development in rare multi-systemic disorders. In our lab we combine rare disease modeling in zebrafish together with cardiovascular and neurobiology techniques and human iPSC-derived brain organoids and endothelial cells.

Responsibilities: The role involves managing day-to-day operations of the lab, perform experiments and report results. The ideal candidate will also help build the lab in a world-leading scientific environment here at the CReM. This position will provide a unique opportunity to build a skill set based on organizational, managerial and hands-on experience in setting up a new lab.

Specific duties will involve:

  • Cell culture (iPSCs) maintenance, expansion and characterization and routine mycoplasma testing
  • Maintain zebrafish colonies, genotypification of fish lines and zebrafish embryos handling
  • Perform standard Molecular Biology techniques such as qPCR, PCR, Western-blot, in situ hybridization and cloning
  • Plan, assist and conduct research, including collection and recording of results, information and samples
  • Ensure the lab establishes and maintains a calibration program for testing equipment that affect quality results
  • Data analysis, presentation and report preparation

Required qualifications:

  • Bachelor’s degree in Biology or a related field
  • Minimum of 1 year of experience in cell culture laboratory and/or 1 year of experience in zebrafish model or 3 years of experience in a molecular biology laboratory
  • Demonstrated record of accomplishment, assisting, initiating and/or completing a research project (poster presentation, scientific communication, publication)
  • Knowledge of molecular Biology techniques: PCR, qPCR, HRMA, western blot, in situ hybridization
  • Collaborative, honest and attention to detail
  • An excellent candidate will exhibit the following:
  • Experience in high throughput single cell techniques like scRNAseq and snATACseq
  • Experience in Confocal microscopy, super resolution microscopy or general imaging systems
  • Experience in statistical and Imaging analysis software like FIJI and Prism
  • Bioinformatics knowledge, R is preferred
  • Experience in zebrafish husbandry
  • Experience in histological techniques

Contact: Please forward a cover letter and a current CV/resume to Gabrielle Cockerham at gabbyac@bu.edu

More information:
Research at CReM
The Serrano Lab

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