Decoding the Centenarians’ Secret to Disease Resistance and Longevity

To keep up with the world’s rapidly aging population, the NAM launched the Healthy Longevity Global Competition, a multi-stage global competition designed to seek out bold, innovative, and breakthrough ideas that challenge the way we think about aging. The Catalyst Award, the first stage of the competition, rewards exciting opportunities that display prospective improvement in the mental, physical, and social well-being of individuals as they age. George Murphy is one of NAM’s 46 U.S.-based Catalyst Awardees. We hear from George, co-founder of the Boston University and Boston Medical Center’s Center for Regenerative Medicine (CReM), who speaks to the award-winning project seeking solutions in regenerative medicine to extend the human health span.

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Our research focuses on understanding how lung epithelial progenitors interact with their supportive niche in the contexts of pulmonary disease and repair. We use cell culture, mouse models, and cell engraftment to study and augment these interactions with the ultimate goal of establishing novel therapies for pulmonary disease.

In addition, it is our mission to foster a welcoming and supportive environment, both within our lab and the wider research community, in order to train the next generation of scientists. We strongly believe that a diverse and collaborative community is an essential foundation for exploring the world around us and developing effective treatments for patients.