Kotton and colleagues generate human alveolar epithelial type I cells (AT1s) from induced pluripotent stem cells (iPSCs). The resulting cells can be grown as 3D organoids or in 2D air-liquid interface cultures, displaying many of the molecular, morphologic, and functional phenotypes of primary AT1s.
Click here to read the article. Alveolar epithelial type I cells (AT1s) line the gas
Kotton and colleagues generate human alveolar epithelial type I cells (AT1s) from induced pluripotent stem
A team of researchers led by Darrell N. Kotton, MD, the David C. Seldin Professor
Mutations in ATP-binding cassette A3 (ABCA3), a phospholipid transporter critical for surfactant homeostasis in pulmonary
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